PNT (Positioning, Navigation, and Timing) for activity extending seamlessly from Earth surface through the LEO, MEO, GEO, and beyond until the surface of the moon is now at the forefront of space capabilities development and space exploration. The foundational building blocks for this are terrestrial and lunar reference frames, integrated across the cislunar space. The sea-level science driven discipline of the recent past is now equally driven by emerging PNT needs. We are tackling new problems ranging from orbit determination to integration of lunar/terrestrial reference frames.